Prevalence and resistance profile to antibiotics of diabetic foot infections isolated microorganisms

Diabetes mellitus (DM) is a chronic disease that affects a considerable portion of the population and type 2 diabetes represents a serious current public health problem in Mexico. Diabetic foot is a severe consequence of diabetes for its prevalence, the frequency of resulting infections, and the hig...

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Main Authors:	Bocanegra-García, Virgilio, Hernández-Gracía, Guillermo, Cantú-Ramírez, Rubén Celerino, Díaz-López, Arely, Ávila-Aguilar, Selene, Espinoza-Tavera, Alejandro, García-García, Edgar Alonso, Rivera-Sánchez, Gildardo
Format:	Online
Language:	eng
Published:	Universidad Autónoma de Tamaulipas 2014
Online Access:	https://revistaciencia.uat.edu.mx/index.php/CienciaUAT/article/view/628
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spelling	oai:ojs.pkp.sfu.ca:article-6282015-12-09T12:10:28Z Prevalence and resistance profile to antibiotics of diabetic foot infections isolated microorganisms Prevalencia y perfil de resistencia a antibióticos de microorganismos aislados de infecciones en pie diabético Bocanegra-García, Virgilio Hernández-Gracía, Guillermo Cantú-Ramírez, Rubén Celerino Díaz-López, Arely Ávila-Aguilar, Selene Espinoza-Tavera, Alejandro García-García, Edgar Alonso Rivera-Sánchez, Gildardo diabetic foot infections drug-resistance. pie diabético infecciones fármaco-resistencia. Diabetes mellitus (DM) is a chronic disease that affects a considerable portion of the population and type 2 diabetes represents a serious current public health problem in Mexico. Diabetic foot is a severe consequence of diabetes for its prevalence, the frequency of resulting infections, and the high social and economic costs. In this study we examined 382 isolated families of infections in 284 patients to determine their identity by biochemical tests and their drug resistance profile. Of the 382 isolates, 186 samples (48.6 %) were positive Gram bacteria; 182 samples (47.6 %) were negative Gram bacteria; and 14 (3.6 %) were Candida sp. In 158 of the 284 samples (55.6.%) only one type of bacteria was identified; in 113 samples (39.7 %) a mixed culture was found, with 7 samples containing both bacteria and yeast and 13 samples resulting negative. The most prevalent pathogens were Staphylococcus aureus and Pseudomonas aeruginosa. In S. aureus isolates, 63.9 % was resistant to MRSA; 4.1 % was resistant to vancomicyn; and 18.6 % was resistant to imepenem. P. aeruginosa was the most prevalent Gram negative isolated and also the one with the most drug resistance. Drug-resistance analysis showed that the majority of S. aureus were MRSA and in P. aeruginosa, families resistant to all tested antimicrobials prevailed. La diabetes mellitus (DM) es una enfermedad crónica que afecta a un porcentaje considerable de la población, y la diabetes tipo II constituye un gran problema de salud pública en México actualmente. El pie diabético es una secuela grave de la diabetes por su prevalencia, la frecuencia con que se presentan infecciones y por los enormes costos económicos y sociales. En este estudio se examinaron 382 cepas aisladas de infecciones a partir de 284 pacientes con pie diabético, para determinar su identidad mediante pruebas bioquímicas y perfil de fármaco-resistencia. De las 382 cepas, 186 (48.6 %) fueron bacterias Gram positivas, 182 (47.6 %) bacterias Gram negativas y 14 (3.6 %) Candida sp. En 158 de las 284 muestras (55.6 %), se obtuvo solo un tipo de bacteria en 113 muestras (39.7 %); se obtuvo un cultivo mixto, y dentro de estas, 7 tenían crecimiento de bacteria y levadura y 13 muestras resultaron negativas. Los patógenos más prevalentes fueron Staphylococcus aureus y Pseudomonas aeruginosa. El 63.9 % de los aislados de S. aureus resultó resistente a la meticilina (MRSA), 44.1% resistentes a la vancomicina y un 18.6% resistentes al imipenem. P. aeruginosa fue el Gram negativo aislado con mayor frecuencia, mostrando multifármaco-resistencia. Los perfiles de fármaco-resistencia mostraron que la mayoría de S. aureus fue MRSA y en los aislados de P. aeruginosa prevalecieron las cepas resistentes a todos los antibióticos probados. Universidad Autónoma de Tamaulipas 2014-12-10 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://revistaciencia.uat.edu.mx/index.php/CienciaUAT/article/view/628 10.29059/cienciauat.v9i1.628 CienciaUAT; Vol. 9 No. 1: July-December 2014; 84-89 CienciaUAT; Vol. 9 No. 1: Julio-Diciembre 2014; 84-89 2007-7858 2007-7521 eng https://revistaciencia.uat.edu.mx/index.php/CienciaUAT/article/view/628/347
institution	CIENCIA UAT
collection	OJS
language	eng
format	Online
author	Bocanegra-García, Virgilio Hernández-Gracía, Guillermo Cantú-Ramírez, Rubén Celerino Díaz-López, Arely Ávila-Aguilar, Selene Espinoza-Tavera, Alejandro García-García, Edgar Alonso Rivera-Sánchez, Gildardo
spellingShingle	Bocanegra-García, Virgilio Hernández-Gracía, Guillermo Cantú-Ramírez, Rubén Celerino Díaz-López, Arely Ávila-Aguilar, Selene Espinoza-Tavera, Alejandro García-García, Edgar Alonso Rivera-Sánchez, Gildardo Prevalence and resistance profile to antibiotics of diabetic foot infections isolated microorganisms
author_facet	Bocanegra-García, Virgilio Hernández-Gracía, Guillermo Cantú-Ramírez, Rubén Celerino Díaz-López, Arely Ávila-Aguilar, Selene Espinoza-Tavera, Alejandro García-García, Edgar Alonso Rivera-Sánchez, Gildardo
author_sort	Bocanegra-García, Virgilio
title	Prevalence and resistance profile to antibiotics of diabetic foot infections isolated microorganisms
title_short	Prevalence and resistance profile to antibiotics of diabetic foot infections isolated microorganisms
title_full	Prevalence and resistance profile to antibiotics of diabetic foot infections isolated microorganisms
title_fullStr	Prevalence and resistance profile to antibiotics of diabetic foot infections isolated microorganisms
title_full_unstemmed	Prevalence and resistance profile to antibiotics of diabetic foot infections isolated microorganisms
title_sort	prevalence and resistance profile to antibiotics of diabetic foot infections isolated microorganisms
description	Diabetes mellitus (DM) is a chronic disease that affects a considerable portion of the population and type 2 diabetes represents a serious current public health problem in Mexico. Diabetic foot is a severe consequence of diabetes for its prevalence, the frequency of resulting infections, and the high social and economic costs. In this study we examined 382 isolated families of infections in 284 patients to determine their identity by biochemical tests and their drug resistance profile. Of the 382 isolates, 186 samples (48.6 %) were positive Gram bacteria; 182 samples (47.6 %) were negative Gram bacteria; and 14 (3.6 %) were Candida sp. In 158 of the 284 samples (55.6.%) only one type of bacteria was identified; in 113 samples (39.7 %) a mixed culture was found, with 7 samples containing both bacteria and yeast and 13 samples resulting negative. The most prevalent pathogens were Staphylococcus aureus and Pseudomonas aeruginosa. In S. aureus isolates, 63.9 % was resistant to MRSA; 4.1 % was resistant to vancomicyn; and 18.6 % was resistant to imepenem. P. aeruginosa was the most prevalent Gram negative isolated and also the one with the most drug resistance. Drug-resistance analysis showed that the majority of S. aureus were MRSA and in P. aeruginosa, families resistant to all tested antimicrobials prevailed.
publisher	Universidad Autónoma de Tamaulipas
publishDate	2014
url	https://revistaciencia.uat.edu.mx/index.php/CienciaUAT/article/view/628
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Prevalence and resistance profile to antibiotics of diabetic foot infections isolated microorganisms

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