Dengue virus: structura, serotypes and molecular epidimilogy
Dengue fever is one of the most important viral diseases in the world. Dengue virus is transmitted to humans by Aedes aegypti mosquitoes. This virus is the causative agent of dengue fever and severe forms: dengue hemorrhagic fever and Dengue shock syndrome. There are four dengue virus serotypes. The...
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2012
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oai:ojs.pkp.sfu.ca:article-542017-11-23T18:00:04Z Dengue virus: structura, serotypes and molecular epidimilogy Virus del dengue: estructura de serotipos y epidemiología molecular Laredo Tiscareño, Stephanie Viridiana Guo, Xianwu Bocanegra García, Virgilio Dengue serotypes genotypes endemic regions genomic variants. Dengue serotipos genotipos regiones endémicas variantes genómicas. Dengue fever is one of the most important viral diseases in the world. Dengue virus is transmitted to humans by Aedes aegypti mosquitoes. This virus is the causative agent of dengue fever and severe forms: dengue hemorrhagic fever and Dengue shock syndrome. There are four dengue virus serotypes. The virus spreads in two transmission cycles and considering the source of these infections, is classifi ed as urban and sylvatic. During viral infection and replication, eight proteins are involved in the generation and release of new viruses mature and infectious. In Mexico the first outbreaks of dengue virus appeared in 1941, getting re-emerge in 1978. Recently circulation of all four serotypes of dengue virus in Mexico has been confirmed. Each serotype has different grades of genetic diversity that raise several genotypes. These viral genotypes, contain several alterations in the order of the nucleotidic sequences. The study of the distribution of these genomic variants adds another level of complexity to the study of dengue infection in humans. The article illustrates the importance of Epidemiological of dengue disease and the genotypes that make up the dengue virus serotypes. El dengue es una de las enfermedades virales más importantes en el mundo. El virus del dengue es transmitido a los humanos por la picadura de mosquitos del género Aedes aegypti. Este virus es el agente causal de la fi ebre por dengue, así como sus formas severas: fiebre hemorrágica por dengue y síndrome de shock por dengue. Existen cuatros serotipos del virus del dengue. El virus se dispersa en dos ciclos de transmisión y considerando el origen de estas infecciones, se clasifica como selvático y urbano. Durante la infección y replicación viral, ocho proteínas son las que están involucradas en la generación y liberación de los nuevos virus maduros e infecciosos. En México los primeros brotes del virus del dengue aparecieron en 1941, consiguiendo re-emerger en 1978. Recientemente se ha confirmado la circulación de los cuatro serotipos del virus del dengue en México. El artículo ilustra la importancia de los genotipos que componen a los serotipos del virus del dengue. Estos genotipos virales, contienen varias alteraciones en las secuencias nucleotídicas. El estudio de la distribución de estas variantes genómicas añade un nuevo nivel de complejidad al estudio de la infección por dengue en humanos. Universidad Autónoma de Tamaulipas 2012-06-30 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://revistaciencia.uat.edu.mx/index.php/CienciaUAT/article/view/54 10.29059/cienciauat.v6i3.54 CienciaUAT; Vol. 6 No. 3: January-June 2012; 27-33 CienciaUAT; Vol. 6 No. 3: Enero-Junio 2012; 27-33 2007-7858 2007-7521 eng https://revistaciencia.uat.edu.mx/index.php/CienciaUAT/article/view/54/44 |
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CIENCIA UAT |
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eng |
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Online |
author |
Laredo Tiscareño, Stephanie Viridiana Guo, Xianwu Bocanegra García, Virgilio |
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Laredo Tiscareño, Stephanie Viridiana Guo, Xianwu Bocanegra García, Virgilio Dengue virus: structura, serotypes and molecular epidimilogy |
author_facet |
Laredo Tiscareño, Stephanie Viridiana Guo, Xianwu Bocanegra García, Virgilio |
author_sort |
Laredo Tiscareño, Stephanie Viridiana |
title |
Dengue virus: structura, serotypes and molecular epidimilogy |
title_short |
Dengue virus: structura, serotypes and molecular epidimilogy |
title_full |
Dengue virus: structura, serotypes and molecular epidimilogy |
title_fullStr |
Dengue virus: structura, serotypes and molecular epidimilogy |
title_full_unstemmed |
Dengue virus: structura, serotypes and molecular epidimilogy |
title_sort |
dengue virus: structura, serotypes and molecular epidimilogy |
description |
Dengue fever is one of the most important viral diseases in the world. Dengue virus is transmitted to humans by Aedes aegypti mosquitoes. This virus is the causative agent of dengue fever and severe forms: dengue hemorrhagic fever and Dengue shock syndrome. There are four dengue virus serotypes. The virus spreads in two transmission cycles and considering the source of these infections, is classifi ed as urban and sylvatic. During viral infection and replication, eight proteins are involved in the generation and release of new viruses mature and infectious. In Mexico the first outbreaks of dengue virus appeared in 1941, getting re-emerge in 1978. Recently circulation of all four serotypes of dengue virus in Mexico has been confirmed. Each serotype has different grades of genetic diversity that raise several genotypes. These viral genotypes, contain several alterations in the order of the nucleotidic sequences. The study of the distribution of these genomic variants adds another level of complexity to the study of dengue infection in humans. The article illustrates the importance of Epidemiological of dengue disease and the genotypes that make up the dengue virus serotypes. |
publisher |
Universidad Autónoma de Tamaulipas |
publishDate |
2012 |
url |
https://revistaciencia.uat.edu.mx/index.php/CienciaUAT/article/view/54 |
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1712116100054908928 |