Use of medicinal plants as an alternative for the treatment of fasciolasis

Fascioliasis is a disease produced by parasitic flatworms of the class trematoda and genus Fasciola that affects animals and humans. Despite its considerable impact on public health and the livestock, as well as its frequent reappearance, it is among the neglected tropical diseases. Furthermore, the...

Full description

Saved in:

Bibliographic Details
Main Authors:	Licona-Hernández, Joseline, Olave-Leyva, José Ignacio, Ojeda-Ramírez, Deyanira
Format:	Online
Language:	spa
Published:	Universidad Autónoma de Tamaulipas 2024
Online Access:	https://revistaciencia.uat.edu.mx/index.php/CienciaUAT/article/view/1846
Tags:	Add Tag No Tags, Be the first to tag this record!

id	oai:ojs.pkp.sfu.ca:article-1846
record_format	ojs
spelling	oai:ojs.pkp.sfu.ca:article-18462024-07-20T01:00:24Z Use of medicinal plants as an alternative for the treatment of fasciolasis Uso de plantas medicinales como una alternativa para el tratamiento de la fasciolasis Licona-Hernández, Joseline Olave-Leyva, José Ignacio Ojeda-Ramírez, Deyanira Fasciola medicinal plants extracts secondary metabolites Fasciola plantas medicinales extractos metabolitos secundarios Fascioliasis is a disease produced by parasitic flatworms of the class trematoda and genus Fasciola that affects animals and humans. Despite its considerable impact on public health and the livestock, as well as its frequent reappearance, it is among the neglected tropical diseases. Furthermore, the indiscriminate use of synthetic fasciolicides in livestock has led to resistance of this trematode to the anthelmintics available on the market. For that, it is necessary to have new treatment alternatives. The aim of this work was to analyze recent advances worldwide on medicinal plants with an effect on Fasciola, reported in PubMed, Scopus, SciFinder and Google Scholar databases, between January 2019 and July 2023. We found information of 32 fasciolicide plants: seven of them with activity on eggs, three on larval stages, one on juveniles, and the rest on the adult stage of the parasite. Among the secondary metabolites responsible for the pharmacological activity, monoterpenes, alkaloids, polyunsaturated fatty acids (PUFA’s), artemisin and phenolic compounds have been identified, highlighting curcumin and thymoquine. The findings reveal the potential use of plants as a source of new fasciolicidal active ingredients. La fascioliasis es una enfermedad causada por gusanos planos, parásitos de la clase trematoda y género Fasciola, que afecta a animales y humanos. A pesar de su considerable impacto en la salud pública y el sector pecuario, así como a su frecuente reaparición, se encuentra entre las enfermedades tropicales desatendidas. Aunado a ello, el uso indiscriminado de fasciolicidas sintéticos en el ganado ha propiciado resistencia de este trematodo a los antihelmínticos disponibles en el mercado, por lo que es necesario contar con nuevas alternativas de tratamiento. El objetivo de este trabajo fue analizar los avances recientes a nivel mundial sobre las plantas medicinales con efecto sobre Fasciola, reportadas en las bases de datos PubMed, Scopus, SciFinder y Google Scholar, entre enero de 2019 y julio de 2023. Se encontraron reportes sobre el potencial fasciolicida de 32 plantas, 7 de ellas con actividad sobre huevos, 3 sobre los estadios larvales, 1 sobre juveniles y el resto sobre el estadio adulto del parásito. Dentro de los metabolitos secundarios responsables de la actividad farmacológica, se han identificado monoterpenos, alcaloides, ácidos grasos poliinsaturados (PUFA’s), artemisina y compuestos fenólicos; destacando la curcumina y la timoquinona. Los resultados encontrados ponen de manifiesto el potencial uso de las plantas como fuente de nuevos principios activos fasciolicidas. Universidad Autónoma de Tamaulipas 2024-03-22 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf text/html https://revistaciencia.uat.edu.mx/index.php/CienciaUAT/article/view/1846 10.29059/cienciauat.v19i1.1846 CienciaUAT; Vol. 19, No. 1. July-December 2024; 61-73 CienciaUAT; Vol. 19, No. 1: julio-diciembre 2024; 61-73 2007-7858 2007-7521 spa https://revistaciencia.uat.edu.mx/index.php/CienciaUAT/article/view/1846/1224 https://revistaciencia.uat.edu.mx/index.php/CienciaUAT/article/view/1846/1193 Derechos de autor 2024 Universidad Autónoma de Tamaulipas https://creativecommons.org/licenses/by-nc-sa/4.0
institution	CIENCIA UAT
collection	OJS
language	spa
format	Online
author	Licona-Hernández, Joseline Olave-Leyva, José Ignacio Ojeda-Ramírez, Deyanira
spellingShingle	Licona-Hernández, Joseline Olave-Leyva, José Ignacio Ojeda-Ramírez, Deyanira Use of medicinal plants as an alternative for the treatment of fasciolasis
author_facet	Licona-Hernández, Joseline Olave-Leyva, José Ignacio Ojeda-Ramírez, Deyanira
author_sort	Licona-Hernández, Joseline
title	Use of medicinal plants as an alternative for the treatment of fasciolasis
title_short	Use of medicinal plants as an alternative for the treatment of fasciolasis
title_full	Use of medicinal plants as an alternative for the treatment of fasciolasis
title_fullStr	Use of medicinal plants as an alternative for the treatment of fasciolasis
title_full_unstemmed	Use of medicinal plants as an alternative for the treatment of fasciolasis
title_sort	use of medicinal plants as an alternative for the treatment of fasciolasis
description	Fascioliasis is a disease produced by parasitic flatworms of the class trematoda and genus Fasciola that affects animals and humans. Despite its considerable impact on public health and the livestock, as well as its frequent reappearance, it is among the neglected tropical diseases. Furthermore, the indiscriminate use of synthetic fasciolicides in livestock has led to resistance of this trematode to the anthelmintics available on the market. For that, it is necessary to have new treatment alternatives. The aim of this work was to analyze recent advances worldwide on medicinal plants with an effect on Fasciola, reported in PubMed, Scopus, SciFinder and Google Scholar databases, between January 2019 and July 2023. We found information of 32 fasciolicide plants: seven of them with activity on eggs, three on larval stages, one on juveniles, and the rest on the adult stage of the parasite. Among the secondary metabolites responsible for the pharmacological activity, monoterpenes, alkaloids, polyunsaturated fatty acids (PUFA’s), artemisin and phenolic compounds have been identified, highlighting curcumin and thymoquine. The findings reveal the potential use of plants as a source of new fasciolicidal active ingredients.
publisher	Universidad Autónoma de Tamaulipas
publishDate	2024
url	https://revistaciencia.uat.edu.mx/index.php/CienciaUAT/article/view/1846
work_keys_str_mv	AT liconahernandezjoseline useofmedicinalplantsasanalternativeforthetreatmentoffasciolasis AT olaveleyvajoseignacio useofmedicinalplantsasanalternativeforthetreatmentoffasciolasis AT ojedaramirezdeyanira useofmedicinalplantsasanalternativeforthetreatmentoffasciolasis AT liconahernandezjoseline usodeplantasmedicinalescomounaalternativaparaeltratamientodelafasciolasis AT olaveleyvajoseignacio usodeplantasmedicinalescomounaalternativaparaeltratamientodelafasciolasis AT ojedaramirezdeyanira usodeplantasmedicinalescomounaalternativaparaeltratamientodelafasciolasis
_version_	1817480082371903488

Use of medicinal plants as an alternative for the treatment of fasciolasis

Similar Items